account_balance
Investment manager · 13F filer · SEC CIK 2005245
Siren, L.l.c.
Reported value$4.22Bas of Sep 30, 2026
Positions110 16 new, 21 sold out
Top 10 weight47.4%SRRK alone is 11%
FiledNov 1243 days after quarter end
Portfolio · as of Sep 30, 2026
Where the money is
New or addedTrimmedHeld
SRRKScholar Rock Holding Corporation
10.7%Trimmed −2%
KYMRKymera Therapeutics, Inc.
7.4%Trimmed −5%
ERASErasca, Inc.
4.6%Added +16%
RVMDRevolution Medicines, Inc.
4.1%Trimmed −6%
ONCBeOne Medicines AG
4.0%
TNGXTango Therapeutics, Inc.
4.0%Added +10%
MANEVeradermics, Incorporated
3.8%Trimmed −20%
ARWRArrowhead Pharmaceuticals, Inc.
3.6%Added +34%
EWTXEdgewise Therapeutics, Inc.
2.7%Trimmed −12%
RYTMRhythm Pharmaceuticals, Inc.
2.5%Trimmed −4%
BCAXBicara Therapeutics Inc
2.4%
PBLSParabilis Medicines Inc
2.3%
SRRKScholar Rock Holding Corporation
10.7%Trimmed −2%
KYMRKymera Therapeutics, Inc.
7.4%Trimmed −5%
ERASErasca, Inc.
4.6%Added +16%
RVMDRevolution Medicines, Inc.
4.1%Trimmed −6%
ONCBeOne Medicines AG
4.0%
TNGX4.0%MANE3.8%ARWR3.6%EWTX2.7%RYTM2.5%BCAX2.4%PBLS2.3%Boxes show the top 12 stocks, sized against each other. The bar above shows how much of the fund they are. 13F only covers US-listed stocks, so foreign holdings and short positions are missing.
Show the top 12 as a list
SRRK Scholar Rock Holding Corporation 10.7% Trimmed −2%KYMR Kymera Therapeutics, Inc. 7.4% Trimmed −5%ERAS Erasca, Inc. 4.6% Added +16%RVMD Revolution Medicines, Inc. 4.1% Trimmed −6%ONC BeOne Medicines AG 4.0% HeldTNGX Tango Therapeutics, Inc. 4.0% Added +10%MANE Veradermics, Incorporated 3.8% Trimmed −20%ARWR Arrowhead Pharmaceuticals, Inc. 3.6% Added +34%EWTX Edgewise Therapeutics, Inc. 2.7% Trimmed −12%RYTM Rhythm Pharmaceuticals, Inc. 2.5% Trimmed −4%BCAX Bicara Therapeutics Inc 2.4% HeldPBLS Parabilis Medicines Inc 2.3% Held
What changed